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ForumsProgress & Lab Results100 lbs lost in 14 months — 12 month update Page 7

100 lbs lost in 14 months — 12 month update

claudia_zurich Mon, Feb 2, 2026 at 9:02 AM 37 replies 1,305 viewsPage 7 of 8
Dr.PathRoch
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Jun 2024
Rochester, MN
Feb 2, 2026 at 6:57 PM#31

Relevant to 100 lbs lost in 14 months 12 — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 193 → 93 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Feb 3, 2026 at 12:57 AM
8 11MikeFit_NJ, InsuranceTom, WendyG_ATL and 5 others
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AussieAnna
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Jun 2024
Sydney, AU
Feb 2, 2026 at 7:14 PM#32

Want to share my personal experience related to 100 lbs lost in 14 months 12 since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 279 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 79 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The 100 lbs lost in 14 aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Feb 2, 2026 at 8:14 PM
36 1HPLC_Greg, LibrarianMeg, bri_stats and 33 others
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claudia_zurich
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Jul 2024
Zurich, CH
Feb 2, 2026 at 7:31 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 100 lbs lost in 14 months.

To answer claudia_zurich: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

16 12Dr.LipidDallas, alex_tucson, kevin_tulsa and 13 others
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NurseKim_ATL
Senior Member
1,678
7,234
Feb 2024
Atlanta, GA
Feb 2, 2026 at 7:48 PM#34

Want to share my personal experience related to 100 lbs lost in 14 months 12 since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 251 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 86 lbs, my labs have normalized, and I am off 2 of my 3 medications. The 100 lbs lost in 14 aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Feb 3, 2026 at 12:48 AM
8 2pete_nash, hank_denver, carlos_SATX and 5 others
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bri_stats
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May 2024
Seattle, WA
Feb 2, 2026 at 8:05 PM#35

Dr.PathRoch — that is really helpful context on 100 lbs lost in 14 months. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Last edited: Feb 3, 2026 at 12:05 AM
39 24julia.endo, JessicaM_2024, TomFromTexas and 36 others
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