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ForumsPublic SquareObstructive sleep apnea improvement on GLP-1 — anyone have experience? Page 3

Obstructive sleep apnea improvement on GLP-1 — anyone have experience?

Dr.ObesityLA Fri, Aug 8, 2025 at 12:40 AM 11 replies 1,441 viewsPage 3 of 3
carlos_SATX
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San Antonio, TX
Aug 8, 2025 at 4:55 AM#11

mel_PDX — wow. This community is amazing.

Last edited: Aug 8, 2025 at 6:55 AM
12 19james_edin, FranDenver, Dr.BariatricHTX and 9 others
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PedsEndoPhilly
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Jun 2024
Philadelphia, PA
Aug 8, 2025 at 5:12 AM#12

Slightly tangential to Obstructive sleep apnea but Dr.ObesityLA reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

22 12wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 19 others
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denise_HTX
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Jan 2025
Houston, TX
Aug 8, 2025 at 5:29 AM#13

Thanks for sharing this, Dr.ObesityLA. A few questions about your Obstructive sleep experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Obstructive?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Aug 8, 2025 at 7:29 AM
16 3JessicaH_TX, KevinCompounds, TirzTom and 13 others
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Dr.ObesityLA
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Los Angeles, CA
Aug 8, 2025 at 5:46 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Obstructive sleep apnea.

To answer PedsEndoPhilly: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

3 12chris_chi24, tampaLisa73, KarenAZ_mom
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HPLC_Greg
Senior Member
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Feb 2024
Research Triangle, NC
Aug 8, 2025 at 6:03 AM#15

Relevant to Obstructive sleep apnea — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Aug 8, 2025 at 12:03 PM
38 19SaraMom3, Dr.MetabolicMD, RetaRick_CA and 35 others
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