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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareHas anyone dealt with my 18-month semaglutide journey? Page 2

Has anyone dealt with my 18-month semaglutide journey?

Dr.EndoIndy Tue, Dec 2, 2025 at 7:24 PM 7 replies 986 viewsPage 2 of 2
Dr.KarenChen
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Dec 2, 2025 at 10:14 PM#6
Dr.SportsMedIN said:
— in my experience this comes down to a few key factors

Gonna push back on this one. Has anyone dealt with my 18-month is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

Last edited: Dec 3, 2025 at 4:14 AM
25 11julia.endo, JessicaM_2024, TomFromTexas and 22 others
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dan_philly
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Philadelphia, PA
Dec 2, 2025 at 10:31 PM#7

Adding my data to this Has anyone dealt with my discussion:

MetricBaselineMonth 5Month 6
Weight272 lbs222 lbs197 lbs
A1C6.6%6.0%5.2%
hsCRP6.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

1 22AmyNC_wife
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Dr.PathRoch
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Dec 2, 2025 at 10:48 PM#8

PeptideChemSF — wow. This community is amazing.

Last edited: Dec 3, 2025 at 4:48 AM
10 18WendyG_ATL, SaraMom3, Dr.MetabolicMD and 7 others
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jim_asheville
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Asheville, NC
Dec 2, 2025 at 11:05 PM#9

Slightly tangential to Has anyone dealt with my but Dr.NephBHM_UK reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Dec 3, 2025 at 2:05 AM
1 9wanda_boise
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mike_mod
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Dec 2, 2025 at 11:22 PM#10

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

44 12PurityPaulOR, MaxMetOK, MounjBrad and 41 others
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