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ForumsPublic SquareIs there a ceiling effect for GLP-1-mediated weight loss? — my results so far Page 5

Is there a ceiling effect for GLP-1-mediated weight loss? — my results so far

raj_cambridge Mon, Dec 15, 2025 at 6:20 AM 33 replies 1,411 viewsPage 5 of 7
mike_mealprep
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Dec 15, 2025 at 1:25 PM#21

Reading this thread on Is there a ceiling effect hits close to home. Night shift nurse — I started at 295 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 70 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Is there a ceiling — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Dec 15, 2025 at 7:25 PM
5 21mia_MS2, LeilaHI, marcus_mpls and 2 others
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Admin
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Dec 15, 2025 at 1:42 PM#22

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Dec 15, 2025 at 5:42 PM
31 13SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 28 others
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FDA_TrackerJim
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Dec 15, 2025 at 1:59 PM#23

Relevant to Is there a ceiling effect for — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 207 → 107 mg/dL, hsCRP 6.0 → 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

21 8MikeNYC_runner and 18 others
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NeuroNate
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Dec 15, 2025 at 2:16 PM#24

Thank you KetoKyle! This is incredibly helpful. Bookmarking for later. 🙏

25 11kim_atl_prep, sarah_TO, wendy_avl and 22 others
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SteveThurs
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Dec 15, 2025 at 2:33 PM#25

+1 to MeganSA_TX. Especially the point about "Is there a ceiling effect is exactly wha..." — I have seen the same in my own experience with Is there a ceiling effect.

16 23TomTeleRx, DoseLogDan, SleepFixSam and 13 others
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