OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Compounded sema shortage .
To answer Dr.EM_Chicago: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Relevant to Compounded sema shortage — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
100%. My provider said the same thing about Compounded sema.
Slightly tangential to Compounded sema shortage but FranDenver reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
PharmHunterJen said:Thank you all for the thoughtful replies on Compounded sema shortage
This is exactly right. PharmHunterJen articulated what I have been trying to explain to my doctor for months. The Compounded sema shortage aspect is the most important factor.