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ForumsSide Effects & ManagementNausea incidence by dose tier — my results so far Page 7

Nausea incidence by dose tier — my results so far

MikeFit_NJ Mon, Jul 22, 2024 at 7:15 AM 52 replies 2,374 viewsPage 7 of 11
Dr.SleepRoch
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Rochester, MN
Jul 22, 2024 at 5:10 PM#31

To answer RegAffairsDC's question specifically:

From a clinical standpoint, Nausea incidence by dose tier is something I discuss with patients regularly.

The short answer: discuss this specific situation with your prescribing provider.

The longer answer involves weighing the risk-benefit ratio for your individual situation, which I am happy to elaborate on if helpful.

Last edited: Jul 22, 2024 at 9:10 PM
20 3sarah_TO, wendy_avl, jason_paloalto and 17 others
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Dr.PulmRoch
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Rochester, MN
Jul 22, 2024 at 5:27 PM#32

Slightly tangential to Nausea incidence by dose but RegAffairsDC reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Jul 22, 2024 at 6:27 PM
5 9traveltech_sara, AttorneyGrant, DebRD_ATL and 2 others
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MikeFit_NJ
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Apr 2024
New Jersey
Jul 22, 2024 at 5:44 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Nausea incidence by dose.

To answer MikeFit_NJ: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jul 22, 2024 at 8:44 PM
20 23DeniseRN_TPA, SandraNC_45, Dr.EndoIndy and 17 others
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SarahChen_PharmD
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Dec 2023
San Diego, CA
Jul 22, 2024 at 6:01 PM#34

Reading this thread on Nausea incidence by dose hits close to home. Night shift nurse — I started at 283 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 58 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Nausea incidence by — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Jul 22, 2024 at 9:01 PM
34 21TinaHashiRN, robert_kc, dan_philly and 31 others
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Dr.PeteFamMed
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Jan 2024
Minneapolis, MN
Jul 22, 2024 at 6:18 PM#35

Adding my data to this Nausea incidence by dose discussion:

MetricBaselineMonth 3Month 8
Weight254 lbs234 lbs219 lbs
A1C6.8%5.8%5.4%
hsCRP8.02.01.2

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

15 24FranDenver, Dr.BariatricHTX, LindaRN_retired and 12 others
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