Sep 26, 2025 at 1:03 PM#11
MaxMetOK — wow. This community is amazing.
Last edited: Sep 26, 2025 at 7:03 PM
16 5mia_MS2, LeilaHI, marcus_mpls and 13 others
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Sep 26, 2025 at 1:20 PM#12
Slightly tangential to 18-month transformation but GenomicsKate reminded me — what is the latest on the oral formulations?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Last edited: Sep 26, 2025 at 6:20 PM
34 10Dr.NateNeph, PharmD_Rodriguez, julia.endo and 31 others
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Sep 26, 2025 at 1:37 PM#13
Thanks for sharing this, GenomicsKate. A few questions about your 18-month transformat experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about 18-month transf?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
21 9HPLC_Greg, LibrarianMeg, bri_stats and 18 others
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Sep 26, 2025 at 1:54 PM#14
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 18-month transformation .
To answer andrew_nyc: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Last edited: Sep 26, 2025 at 6:54 PM
18 16Dr.PeteFamMed, claudia_zurich, nancy_portland and 15 others
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Sep 26, 2025 at 2:11 PM#15
Relevant to 18-month transformation my — here is my latest bloodwork comparison:
Key improvements: A1C 7.6% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
44 23RickReta_CO, PharmHunterJen, TomTeleRx and 41 others
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