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ForumsMASH / Liver DiseaseLiver biopsy changes on semaglutide — looking for input Page 6

Liver biopsy changes on semaglutide — looking for input

Dr.GutHealth Sat, Oct 19, 2024 at 8:18 AM 29 replies 2,184 viewsPage 6 of 6
PharmHunterJen
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Oct 19, 2024 at 4:48 PM#26

+1 to fiona_glasgow. Especially the point about "This is incredibly helpful..." — I have seen the same in my own experience with Liver biopsy changes on.

7 1Dr.LipidDallas, alex_tucson, kevin_tulsa and 4 others
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TomFromTexas
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May 2024
Austin, TX
Oct 19, 2024 at 5:05 PM#27

Bookmarked 📌 The Liver biopsy changes info in this thread is essential. Coming back to this for sure.

11 21Dr.NateNeph, PharmD_Rodriguez, julia.endo and 8 others
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Dr.PulmRoch
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Rochester, MN
Oct 19, 2024 at 5:22 PM#28

Clinical perspective on Liver biopsy changes on semaglutide :

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: Oct 19, 2024 at 6:22 PM
1 11AttorneyGrant
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jim_asheville
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Oct 19, 2024 at 5:39 PM#29

Want to share my personal experience related to Liver biopsy changes on since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 252 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 47 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Liver biopsy changes aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

4 2wanda_boise, NurseAsh_DET, BenResearch_OR and 1 other
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greg_boulder
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Boulder, CO
Oct 19, 2024 at 5:56 PM#30

Just wanted to say — for anyone reading this Liver biopsy changes thread who is feeling discouraged: it gets better. The first 6 weeks are the hardest. Hang in there. 💪

Last edited: Oct 19, 2024 at 7:56 PM
36 1ben_calgary, patPC_UT, Dr.DermMIA and 33 others
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