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ForumsMASH / Liver DiseaseHas anyone dealt with fibrosis regression on glp-1? Page 3

Has anyone dealt with fibrosis regression on glp-1?

JenMemphis Sat, Apr 26, 2025 at 7:21 PM 46 replies 1,810 viewsPage 3 of 10
Admin
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Apr 26, 2025 at 11:36 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Apr 27, 2025 at 3:36 AM
28 5PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 25 others
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jim_asheville
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Apr 26, 2025 at 11:53 PM#12

Clinical perspective on Has anyone dealt with fibrosis:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

Last edited: Apr 27, 2025 at 2:53 AM
46 14BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 43 others
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LabKate
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Apr 27, 2025 at 12:10 AM#13
Admin said:
Consult your healthcare provider

I respect Admin perspective but I think this oversimplifies things a bit. Re: Has anyone dealt with fibrosis — the subgroup analyses show meaningful heterogeneity.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

24 18Dr.SleepRoch, laura_annarbor, JenMemphis and 21 others
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emma_london
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Apr 27, 2025 at 12:27 AM#14

Reading this thread on Has anyone dealt with hits close to home. Night shift nurse — I started at 299 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 74 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Has anyone dealt — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Apr 27, 2025 at 6:27 AM
12 15JessicaM_2024, TomFromTexas, mike.trainer_LA and 9 others
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Dr.NutriCornell
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Apr 27, 2025 at 12:44 AM#15

Bookmarked 📌 The Has anyone dealt info in this thread is essential. Coming back to this for sure.

11 1pat_auckland, Dr.GastroMayo, JakeBK_lifts and 8 others
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