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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionHIIT vs LISS cardio on GLP-1 — looking for input Page 7

HIIT vs LISS cardio on GLP-1 — looking for input

mark_tokyo Sat, Aug 16, 2025 at 11:20 AM 39 replies 1,657 viewsPage 7 of 8
ingrid_STO
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Aug 16, 2025 at 9:15 PM#31

To answer SleepFixSam's question specifically:

From a clinical standpoint, HIIT vs LISS cardio on GLP-1 is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

33 19VendorMark, COA_Karl, MikeFit_NJ and 30 others
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matt_MKE
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Aug 16, 2025 at 9:32 PM#32

Can confirm — same results here.

4 22Dr.EndoEP, GraceAZ_72, carl_compliance and 1 other
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mark_tokyo
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Aug 16, 2025 at 9:49 PM#33

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on HIIT vs LISS cardio on.

To answer mark_tokyo: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

34 17LibrarianMeg, bri_stats, pete_manc_UK and 31 others
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Dr.AddMedPHL
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Aug 16, 2025 at 10:06 PM#34

Subscribing to this thread. HIIT vs LISS cardio on is exactly what I've been researching. 🙏

32 2TomFromTexas, mike.trainer_LA, sarah_nash92 and 29 others
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DataDave
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Washington
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Aug 16, 2025 at 10:23 PM#35

Slightly tangential to HIIT vs LISS cardio on but ingrid_STO reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

45 4Dr.GutHealth, amsterdam_pete, LondonLisa and 42 others
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