Dec 22, 2025 at 4:36 AM#11
RunnerRach — wow. This community is amazing.
Last edited: Dec 22, 2025 at 9:36 AM
11 1anna.melb_AU, mark_tokyo, hans_munich and 8 others
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Dec 22, 2025 at 4:53 AM#12
Slightly tangential to Liver biopsy changes on but jim_asheville reminded me — what is the latest on the oral formulations?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Last edited: Dec 22, 2025 at 9:53 AM
2 10Dr.NateNeph, PharmD_Rodriguez
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Dec 22, 2025 at 5:10 AM#13
Thanks for sharing this, jim_asheville. A few questions about your Liver biopsy changes experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about Liver biopsy?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
50 9Dr.AddMedPHL, newstart_MO, mia_MS2 and 47 others
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Dec 22, 2025 at 5:27 AM#14
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Liver biopsy changes on.
To answer andrew_nyc: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
9 0wanda_boise, NurseAsh_DET, BenResearch_OR and 6 others
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Dec 22, 2025 at 5:44 AM#15
Relevant to Liver biopsy changes on — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
32 8KristenIndy, MarkLI_maint, Dr.PeteFamMed and 29 others
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