May 9, 2026 at 3:34 AM#11
adam_van — wow. This community is amazing.
47 10FitDadDave, RunnerRach, TrialNerd_Beth and 44 others
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May 9, 2026 at 3:51 AM#12
Slightly tangential to Rucking (weighted but FitDadDave reminded me — what is the latest on the oral formulations?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Last edited: May 9, 2026 at 4:51 AM
32 1BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 29 others
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May 9, 2026 at 4:08 AM#13
Thanks for sharing this, FitDadDave. A few questions about your Rucking (weighted experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about Rucking (weight?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
26 24traveltech_sara, AttorneyGrant, DebRD_ATL and 23 others
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May 9, 2026 at 4:25 AM#14
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Rucking (weighted.
To answer NurseLeah_Nash: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
12 4wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 9 others
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May 9, 2026 at 4:42 AM#15
Relevant to Rucking (weighted walking) on — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 229 → 99 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
22 15jason_sac26, chris_chi24, tampaLisa73 and 19 others
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