Feb 24, 2026 at 7:45 AM#6
Subscribing to this thread. Thymosin Beta-4 vs TB-500 is exactly what I've been researching. 🙏
42 4laura_annarbor, JenMemphis, pat_auckland and 39 others
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Feb 24, 2026 at 8:02 AM#7
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Thymosin Beta-4 vs TB-500.
To answer sarah.morrison: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
18 6pete_manc_UK, anna.melb_AU, mark_tokyo and 15 others
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Feb 24, 2026 at 8:19 AM#8
Relevant to Thymosin Beta-4 vs TB-500 — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 197 → 97 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Last edited: Feb 24, 2026 at 9:19 AM
26 5AttorneyGrant, DebRD_ATL, KristenIndy and 23 others
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Feb 24, 2026 at 8:36 AM#9
KarenAZ_mom said:Thank you all for the thoughtful replies on Thymosin Beta-4 vs TB-500
This is exactly right. KarenAZ_mom articulated what I have been trying to explain to my friends for months. The Thymosin Beta-4 vs TB-500 aspect is what made the difference for me.
17 22bri_stats, pete_manc_UK, anna.melb_AU and 14 others
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Feb 24, 2026 at 8:53 AM#10
Slightly tangential to Thymosin Beta-4 vs TB-500 but Dr.GutHealth reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Last edited: Feb 24, 2026 at 2:53 PM
43 19josh_phd_bmore, roxy_nash, tony_orlando and 40 others
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