Slightly tangential to SHBG changes during but TirzTom reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Thanks for sharing this, TirzTom. A few questions about your SHBG changes during experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about SHBG changes?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on SHBG changes during.
To answer mike_mealprep: I get my labs done through Quest every 3 months.
Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Relevant to SHBG changes during weight — here is my latest bloodwork comparison:
Key improvements: A1C 7.2% → 5.3%, triglycerides 223 → 93 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.