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ForumsCardiovascular OutcomesArterial stiffness reduction on GLP-1 — July 2024 Page 5

Arterial stiffness reduction on GLP-1 — July 2024

pat_auckland Wed, Feb 7, 2024 at 4:47 PM 47 replies 2,796 viewsPage 5 of 10
DoseLogDan
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Feb 2025
Montana
Feb 7, 2024 at 11:52 PM#21

Congrats pat_auckland!! Keep going — you're doing incredible. 🎉

6 18newstart_MO, mia_MS2, LeilaHI and 3 others
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mike.trainer_LA
Senior Member
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Apr 2024
Los Angeles, CA
Feb 8, 2024 at 12:09 AM#22

Reading this thread on Arterial stiffness hits close to home. Night shift nurse — I started at 267 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 42 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Arterial stiffness — take the leap. It was the best health decision I have ever made. ❤️

24 22newstart_MO, mia_MS2, LeilaHI and 21 others
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Dr.PulmRoch
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Jun 2024
Rochester, MN
Feb 8, 2024 at 12:26 AM#23

As a pharmacist, I want to add some clinical context to this discussion on Arterial stiffness reduction on GLP-1 .

Building on what DoseLogDan said — the evidence base here is robust. The key publications to reference are from the SELECT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
26 15AttorneyGrant, DebRD_ATL, KristenIndy and 23 others
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LeilaHI
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Jan 2025
Honolulu, HI
Feb 8, 2024 at 12:43 AM#24

mike.trainer_LA — wow. I've been looking for this exact info for weeks.

40 7LondonLisa, mike_nyc, VendorMark and 37 others
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Dr.PeteFamMed
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Jan 2024
Minneapolis, MN
Feb 8, 2024 at 1:00 AM#25

Adding my data to this Arterial stiffness discussion:

MetricBaselineMonth 5Month 6
Weight260 lbs235 lbs215 lbs
A1C6.4%6.0%5.2%
hsCRP4.04.01.0

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.

6 9FranDenver, Dr.BariatricHTX, LindaRN_retired and 3 others
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