Dec 17, 2024 at 3:14 PM#11
Thank you LeilaHI! This is incredibly helpful. Taking this to my next appointment. 🙏
49 1kevin_tulsa, Dr.PainCLE, mike_mealprep and 46 others
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Dec 17, 2024 at 3:31 PM#12
Slightly tangential to NNT for MACE prevention but gary_naperville reminded me — does anyone have experience combining this with metformin?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
36 10stefan_berlin, Dr.EM_Chicago, pete_RVA and 33 others
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Dec 17, 2024 at 3:48 PM#13
Thanks for sharing this, gary_naperville. A few questions about your NNT for MACE experience:
- What dose did you start at?
- How long before you noticed side effects improving?
- Did your provider have any specific recommendations about NNT for MACE?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
Last edited: Dec 17, 2024 at 4:48 PM
48 3maria_elpaso, anders_CPH, Dr.NutriCornell and 45 others
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Dec 17, 2024 at 4:05 PM#14
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on NNT for MACE prevention .
To answer TrialTracker_MD: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
15 11PharmHunterJen, TomTeleRx, DoseLogDan and 12 others
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Dec 17, 2024 at 4:22 PM#15
Adding my data to this NNT for MACE prevention discussion:
| Metric | Baseline | Month 3 | Month 8 |
|---|---|---|---|
| Weight | 262 lbs | 227 lbs | 207 lbs |
| A1C | 6.6% | 5.8% | 5.4% |
| hsCRP | 6.0 | 2.0 | 1.2 |
Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.
39 9jason_sac26, chris_chi24, tampaLisa73 and 36 others
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