Reading this thread on Has anyone dealt with hits close to home. Night shift nurse — I started at 271 lbs and felt like I would tried everything.
7 months on tirz and I am a different person. Not just the 46 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Has anyone dealt — take the leap. It was the best health decision I have ever made. ❤️
As a pharmacist, I want to add some clinical context to this discussion on Has anyone dealt with apob reduction on.
Building on what sarah_TO said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].
Key clinical points:
- Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
- Side effect profile is predictable and usually manageable with standard protocols
- Monitoring should include baseline labs and follow-up at 3-month intervals
- Patient education significantly improves outcomes and adherence
Standard disclaimer: this is educational, not individualized medical advice.
[1] See thread title for relevant study identification.
CryptoCarl — wow. I've been looking for this exact info for weeks.
Adding my data to this Has anyone dealt with discussion:
| Metric | Baseline | Month 5 | Month 6 |
|---|---|---|---|
| Weight | 264 lbs | 219 lbs | 209 lbs |
| A1C | 6.8% | 6.0% | 5.2% |
| hsCRP | 8.0 | 4.0 | 0.6 |
Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.