TRIUMPH program trial design overview — all Phase 3 arms

Saving this for reference. Top-tier content.

Want to share my personal experience related to TRIUMPH program trial design since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 247 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 42 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The TRIUMPH program aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Relevant to TRIUMPH program trial design — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 223 → 93 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to TRIUMPH program trial design since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 264 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 49 lbs, my labs have normalized, and I am off 2 of my 3 medications. The TRIUMPH program aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

FDA_TrackerJim — that is really helpful context on TRIUMPH program trial. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.