Feb 24, 2026 at 6:22 PM#26
+1. This mirrors my journey exactly. The Has anyone dealt discussion here is so valuable.
Last edited: Feb 24, 2026 at 7:22 PM
5 9Dr.SleepRoch, laura_annarbor, JenMemphis and 2 others
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Feb 24, 2026 at 6:39 PM#27
COA_Karl said:I started my GLP-1 journey in October 2024 at 277 lbs with prediabetes and hypertension
Gonna push back on this one. Has anyone dealt with heart failure is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.
Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.
11 8laura_annarbor, JenMemphis, pat_auckland and 8 others
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Feb 24, 2026 at 6:56 PM#28
Want to share my personal experience related to Has anyone dealt with heart since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 283 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 18 months later: I am down 73 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Has anyone dealt aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
Last edited: Feb 24, 2026 at 9:56 PM
1 18marcus_mpls
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Feb 24, 2026 at 7:13 PM#29
Saving this for reference. Quality thread.
34 20matt_MKE, Dr.ReproEndo, lucas_SP_BR and 31 others
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Feb 24, 2026 at 7:30 PM#30
AttorneyGrant — that is really helpful context on Has anyone dealt with. Follow-up question: how long did you wait before increasing your dose?
I am in a similar situation (week 4) and trying to set realistic expectations.
44 24DanielChem_CHI, marco_milano, pam_columbus and 41 others
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