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ForumsCompounding & Formulation503A vs 503B compounding — 6 month update Page 3

503A vs 503B compounding — 6 month update

ricardo_MIA Mon, Oct 27, 2025 at 7:46 PM 12 replies 1,204 viewsPage 3 of 3
paul_denver
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Oct 28, 2025 at 12:01 AM#11

DeniseRN_TPA — wow. This community is amazing.

39 10Dr.LeslieOBGYN, MikeNYC_runner and 36 others
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Dr.RenalNash
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Oct 28, 2025 at 12:18 AM#12

Slightly tangential to 503A vs 503B compounding but ricardo_MIA reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

35 8pam_stl, wei_SG, cory_ATX and 32 others
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chris_chi24
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Sep 2024
Chicago, IL
Oct 28, 2025 at 12:35 AM#13

Thanks for sharing this, ricardo_MIA. A few questions about your 503A vs 503B experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about 503A vs 503B?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Oct 28, 2025 at 3:35 AM
33 19MaxMetOK, MounjBrad, nick_newbie and 30 others
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ricardo_MIA
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Miami, FL
Oct 28, 2025 at 12:52 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on 503A vs 503B compounding .

To answer Dr.RenalNash: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Oct 28, 2025 at 5:52 AM
11 17KetoKyle, CanadaChris, ZaraB_AL and 8 others
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jason_paloalto
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Palo Alto, CA
Oct 28, 2025 at 1:09 AM#15

Relevant to 503A vs 503B compounding 6 — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

18 23Dr.EndoEP, GraceAZ_72, carl_compliance and 15 others
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