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ForumsCompounding & FormulationMy vial looks cloudy - throw it out?? — what worked for you?

My vial looks cloudy - throw it out?? — what worked for you?

Dr.KarenChen Tue, Dec 9, 2025 at 10:19 AM 8 replies 1,020 viewsPage 1 of 2
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Dr.KarenChen
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Dec 9, 2025 at 11:44 AM#1

Just had to share this with someone who would understand — my vial looks cloudy - throw.

Got my latest A1C and I am genuinely emotional right now. 12 months in and the progress is real.

Details in the comments but wanted to start this thread because I think others going through the same thing need to see that it works.

19 6julia.endo, JessicaM_2024, TomFromTexas and 16 others
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LarryQC_SD
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Dec 9, 2025 at 12:01 PM#2

Dr.KarenChen's experience with My vial looks cloudy - resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 60 lbs in 5 months.

One thing I would add that Dr.KarenChen did not mention: the relationship with food fundamentally changed.

17 22paul_denver, TinaHashiRN, robert_kc and 14 others
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Dr.ReproEndo
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Dec 9, 2025 at 12:18 PM#3

Thanks for sharing this, Dr.KarenChen. A few questions about your My vial looks cloudy experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about My vial looks?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

31 22Dr.EndoEP, GraceAZ_72, carl_compliance and 28 others
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Dr.KarenChen
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Dec 9, 2025 at 12:35 PM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on My vial looks cloudy -.

To answer Dr.ReproEndo: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

25 9mike.trainer_LA, sarah_nash92, FitDadDave and 22 others
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FDA_TrackerJim
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Dec 9, 2025 at 12:52 PM#5

Relevant to My vial looks cloudy - throw — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 213 → 113 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Dec 9, 2025 at 3:52 PM
14 2jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 11 others
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