BiostatsBrad said:5%, triglycerides 233 → 103 mg/dL, hsCRP 8
This is exactly right. BiostatsBrad articulated what I have been trying to explain to my doctor for months. The My 503A vs 503B pharmacy aspect is the most important factor.
Relevant to My 503A vs 503B pharmacy — here is my latest bloodwork comparison:
Key improvements: A1C 7.6% → 5.5%, triglycerides 241 → 111 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Thank you carl_compliance! This is incredibly helpful. Taking this to my next appointment. 🙏
Dr.GastroMayo — that is really helpful context on My 503A vs 503B pharmacy. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.
To answer DeniseRN_TPA's question specifically:
From a clinical standpoint, My 503A vs 503B pharmacy is well-supported by the literature.
The short answer: follow the standard titration protocol and reassess at 4-6 weeks.
The longer answer involves pharmacokinetic considerations around steady-state concentrations, which I am happy to elaborate on if helpful.