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ForumsOral GLP-1 AgonistsOral vs injectable GLP-1: bioavailability and efficacy comparison — anyone have experience? Page 4

Oral vs injectable GLP-1: bioavailability and efficacy comparison — anyone have experience?

stefan_berlin Tue, Nov 18, 2025 at 5:28 PM 45 replies 2,165 viewsPage 4 of 9
Dr.SleepRoch
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Nov 18, 2025 at 11:08 PM#16

Congrats TrialNerd_Beth!! Keep going — you're doing incredible. 🎉 👏

45 20sarah_TO, wendy_avl, jason_paloalto and 42 others
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Dr.PeteFamMed
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Jan 2024
Minneapolis, MN
Nov 18, 2025 at 11:25 PM#17

Exactly this. My pharmacist said the same thing about Oral vs injectable.

5 8tommy_boulder, hyun_seoul, jim_asheville and 2 others
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Dr.PathRoch
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Jun 2024
Rochester, MN
Nov 18, 2025 at 11:42 PM#18
TrialNerd_Beth said:
Oral vs injectable GLP-1 is not that straightforward in my experience

This is exactly right. TrialNerd_Beth articulated what I have been trying to explain to my friends for months. The Oral vs injectable GLP-1 aspect is what made the difference for me.

10 2WendyG_ATL, SaraMom3, Dr.MetabolicMD and 7 others
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josh_phd_bmore
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Baltimore, MD
Nov 18, 2025 at 11:59 PM#19

Same experience here with Oral vs injectable GLP-1. Dr.PathRoch described it perfectly.

39 16KarenAZ_mom, zoe_NC, Dr.ObesityLA and 36 others
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InsuranceTom
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Connecticut
Nov 19, 2025 at 12:16 AM#20

Slightly tangential to Oral vs injectable GLP-1 but Dr.PeteFamMed reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

29 17jim_asheville, matt_MKE, Dr.ReproEndo and 26 others
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