Slightly tangential to Peptide degradation but NauseaFreeNow reminded me — what is the latest on the oral formulations?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Thanks for sharing this, NauseaFreeNow. A few questions about your Peptide degradation experience:
- What dose worked best for you?
- How long before you noticed appetite suppression kicking in?
- Did your endo have any specific recommendations about Peptide degrada?
I am in a similar boat and trying to learn from others' experiences before my next appointment.
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Peptide degradation.
To answer mel_PDX: yes, I am on compounded sema from a 503B pharmacy.
Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Relevant to Peptide degradation pathways — here is my latest bloodwork comparison:
Key improvements: A1C 7.6% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.