Oral GLP-1 for elderly patients — swallowing and compliance advantages — Page 2 — Oral GLP-1 Agonists

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Jan 2024

Minneapolis, MN

May 16, 2026 at 8:29 PM#6

Dr.SurgeonPGH said:
I have been dealing with this for several months now, and what I have found is that individual respo

Gonna push back on this one. Oral GLP-1 for elderly patients is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

35 8hyun_seoul, jim_asheville, matt_MKE and 32 others

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labquiet_amy

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Mar 2024

Cambridge, MA

May 16, 2026 at 8:46 PM#7

Adding my data to this Oral GLP-1 for elderly discussion:

Metric	Baseline	Month 5	Month 8
Weight	266 lbs	216 lbs	221 lbs
A1C	7.0%	6.0%	5.4%
hsCRP	5.0	4.0	0.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

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nancy_portland

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Portland, ME

May 16, 2026 at 9:03 PM#8

Dr.PainCLE — wow. I've been looking for this exact info for weeks.

Last edited: May 16, 2026 at 10:03 PM

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emily_PDX

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Nov 2024

Portland, OR

May 16, 2026 at 9:20 PM#9

Slightly tangential to Oral GLP-1 for elderly but TinaHashiRN reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: May 16, 2026 at 11:20 PM

13 14Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 10 others

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