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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPharmacology & MechanismsStructure-activity relationships of GLP-1 analogs — anyone have experience? Page 4

Structure-activity relationships of GLP-1 analogs — anyone have experience?

sarah_TO Wed, Oct 30, 2024 at 10:31 PM 32 replies 1,968 viewsPage 4 of 7
sarah_TO
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Oct 31, 2024 at 4:11 AM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Structure-activity.

To answer MeganSA_TX: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Oct 31, 2024 at 8:11 AM
19 22andrew_nyc, Dr.EndoEP, GraceAZ_72 and 16 others
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Dr.RaviCardio
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Oct 31, 2024 at 4:28 AM#17

Adding my data to this Structure-activity discussion:

MetricBaselineMonth 3Month 8
Weight278 lbs243 lbs213 lbs
A1C7.2%5.8%5.4%
hsCRP7.02.01.2

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

Last edited: Oct 31, 2024 at 5:28 AM
24 24anna.melb_AU, mark_tokyo, hans_munich and 21 others
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RegAffairsDC
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Oct 31, 2024 at 4:45 AM#18

Agreed. My doctor said the same thing about Structure-activity.

48 10hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 45 others
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TrialNerd_Beth
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Bethesda, MD
Oct 31, 2024 at 5:02 AM#19

Slightly tangential to Structure-activity but SleepDoc_PDX reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Oct 31, 2024 at 9:02 AM
19 1DoseLogDan, SleepFixSam, PurityPaulOR and 16 others
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james_edin
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Edinburgh, UK
Oct 31, 2024 at 5:19 AM#20

+1 to sarah_TO. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Structure-activity.

1 0bbq_ray_KC
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