May 25, 2026 at 11:14 AM#16
Congrats Dr.LipidDallas!! Keep going — you're doing incredible. 🎉 👏
42 24NauseaFreeNow, SteveThurs, B12Beth and 39 others
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May 25, 2026 at 11:31 AM#17
Saving this for reference. Top-tier content.
Last edited: May 25, 2026 at 12:31 PM
11 17AmyNC_wife, SkepticalSean, Dr.CardioMD and 8 others
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May 25, 2026 at 11:48 AM#18
Want to share my personal experience related to ATTAIN-2 orforglipron in T2DM since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 259 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 8 months later: I am down 39 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The ATTAIN-2 orforglipro aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
15 10tampaLisa73, KarenAZ_mom, zoe_NC and 12 others
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May 25, 2026 at 12:05 PM#19
Relevant to ATTAIN-2 orforglipron in T2DM — here is my latest bloodwork comparison:
Key improvements: A1C 8.0% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
5 17DebRD_ATL, KristenIndy, MarkLI_maint and 2 others
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May 25, 2026 at 12:22 PM#20
Want to share my personal experience related to ATTAIN-2 orforglipron in T2DM since I think it might help others in a similar situation.
I started my GLP-1 journey in October 2024 at 276 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.
Now, 14 months later: I am down 46 lbs, my labs have normalized, and I am off 2 of my 3 medications. The ATTAIN-2 orforglipro aspect specifically was something that made a big difference in my journey.
This community helped me every step of the way.
Last edited: May 25, 2026 at 5:22 PM
3 7LarryQC_SD, wanda_boise, NurseAsh_DET
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