Jun 23, 2025 at 5:15 PM#11
+1. This mirrors my journey exactly. The GLP-1R expression discussion here is so valuable.
12 23newstart_MO, mia_MS2, LeilaHI and 9 others
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Jun 23, 2025 at 5:32 PM#12
Reading this thread on GLP-1R expression map hits close to home. Night shift nurse — I started at 287 lbs and felt like I would tried everything.
13 months on tirz and I am a different person. Not just the 62 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about GLP-1R expression — take the leap. It was the best health decision I have ever made. ❤️
19 21newstart_MO, mia_MS2, LeilaHI and 16 others
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Jun 23, 2025 at 5:49 PM#13
Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.
Tagging this for the weekly digest. 👍
Last edited: Jun 23, 2025 at 9:49 PM
40 14RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 37 others
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Jun 23, 2025 at 6:06 PM#14
Relevant to GLP-1R expression map looking — here is my latest bloodwork comparison:
Key improvements: A1C 7.2% → 5.3%, triglycerides 199 → 99 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
Last edited: Jun 23, 2025 at 7:06 PM
49 3james_edin, FranDenver, Dr.BariatricHTX and 46 others
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Jun 23, 2025 at 6:23 PM#15
Congrats DoseLogDan!! Keep going — you're doing incredible. 🎉
36 23Dr.NateNeph, PharmD_Rodriguez, julia.endo and 33 others
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