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ForumsDosing & ProtocolsSteady-state concentrations across dose tiers — January 2024 Page 2

Steady-state concentrations across dose tiers — January 2024

Dr.GastroMayo Thu, Dec 5, 2024 at 11:53 AM 11 replies 1,654 viewsPage 2 of 3
anders_CPH
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Dec 5, 2024 at 2:43 PM#6
Dr.RaviCardio said:
For Steady-state concentrations across, here is what the evidence says:The clinical trial data (SELE

Gonna push back on this one. Steady-state concentrations across is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

8 13CryptoCarl, MariaRD, AussieAnna and 5 others
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Dr.PathRoch
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Dec 5, 2024 at 3:00 PM#7

Adding my data to this Steady-state discussion:

MetricBaselineMonth 4Month 8
Weight278 lbs218 lbs223 lbs
A1C7.2%6.2%5.4%
hsCRP7.03.01.2

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.

Last edited: Dec 5, 2024 at 9:00 PM
36 2InsuranceTom, WendyG_ATL, SaraMom3 and 33 others
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JakeSmashed95
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Dec 5, 2024 at 3:17 PM#8

SleepDoc_PDX — wow. I've been looking for this exact info for weeks.

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sarah_nash92
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Nashville, TN
Dec 5, 2024 at 3:34 PM#9

Slightly tangential to Steady-state but ricardo_MIA reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

49 21CanadaChris, ZaraB_AL, JakeSmashed95 and 46 others
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mike_mod
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Dec 5, 2024 at 3:51 PM#10

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

Last edited: Dec 5, 2024 at 5:51 PM
24 5PurityPaulOR, MaxMetOK, MounjBrad and 21 others
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