Sep 18, 2025 at 11:09 PM#26
+1. This mirrors my journey exactly. The Steady-state discussion here is so valuable.
Last edited: Sep 19, 2025 at 4:09 AM
26 5MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 23 others
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Sep 18, 2025 at 11:26 PM#27
roxy_nash said:Dad of 2 checking in — I started at 297 lbs and felt like I would tried everything
I respect roxy_nash perspective but I think this oversimplifies things a bit. Re: Steady-state concentrations — the subgroup analyses show meaningful heterogeneity.
I am not saying roxy_nash wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.
15 22Dr.DermMIA, fiona_VT, denise_HTX and 12 others
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Sep 18, 2025 at 11:43 PM#28
Reading this thread on Steady-state hits close to home. Night shift nurse — I started at 283 lbs and felt like I would tried everything.
9 months on tirz and I am a different person. Not just the 58 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Steady-state — take the leap. It was the best health decision I have ever made. ❤️
Last edited: Sep 19, 2025 at 4:43 AM
19 4PharmD_Rodriguez, julia.endo, JessicaM_2024 and 16 others
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Sep 19, 2025 at 12:00 AM#29
Bookmarked 📌 The Steady-state info in this thread is essential. Coming back to this for sure.
48 3SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 45 others
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Sep 19, 2025 at 12:17 AM#30
JenMemphis — that is really helpful context on Steady-state. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.
2 16mike_mealprep, NicoleRaleigh
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